Kidney Disease Claiming More Lives

THURSDAY, Dec. 6, 2018 (HealthDay News) -- Although fewer Americans are dying from heart disease and cancer, deaths from chronic kidney disease are on the rise, especially among young adults, a new study finds.

"Unfortunately, chronic kidney disease is known as a 'silent epidemic,' because many people don't realize they have it until the disease is at an advanced stage," said senior study author Dr. Ziyad Al-Aly. He's a nephrologist and an assistant professor of medicine at Washington University School of Medicine in St. Louis.

"It is particularly concerning that chronic kidney disease is becoming more common in younger people. This is a remarkable move in the wrong direction," Al-Aly said in a university news release.

Deaths from cancer and cardiovascular disease have declined due to advances in treatment. But no major advances in the treatment of kidney disease have been seen during the past two decades, Al-Aly said.

Instead, chronic kidney disease has risen across the country in the past 15 years and among those aged 20 to 54 -- a group in which the condition used to be uncommon, the researchers noted. Overall, U.S. deaths from kidney disease increased 58 percent -- from about 52,100 in 2002 to 82,500 in 2016.

The researchers suspect that the increase is at least partially due to high-sugar, high-salt diets and the ongoing obesity epidemic. Unhealthy diets increase toxins that kidneys are designed to remove, which may account for the organs wearing out.

The increase in chronic kidney disease varies by state. For example, while all states saw rising rates, they are significantly higher in places with the highest obesity rates, including Alabama, Georgia, Louisiana, Mississippi and West Virginia.

For the study, Al-Aly and his colleagues used the Global Burden of Disease database, which provides information about 350 diseases and injuries by age and gender, as well as more than 80 risk factors in the United States and other countries. For their study, the researchers focused on U.S. data by age from 2002 to 2016.

They found that the rates of chronic kidney disease are increasing faster than the rates of all noninfectious diseases, including cardiovascular disease, cancer, cirrhosis, chronic lung diseases, mental problems and brain diseases.

Deaths from chronic kidney disease among younger adults are still rare, but they are increasing, the researchers found. For people aged 20 to 54, the probability of death from chronic kidney disease increased almost 27 percent, from 100 deaths per 100,000 people in 2002 to 125 deaths per 100,000 in 2016.

Among those aged 55 and older, chronic kidney disease deaths rose nearly 26 percent, from 1,950 deaths per 100,000 people in 2002 to 2,450 deaths per 100,000 in 2016.

"Public health priorities, policy initiatives, funding allocation and advocacy efforts need to catch up to this reality that the burden of chronic kidney disease is rising, and the speed of change now outpaces other noncommunicable diseases," Al-Aly said. "A concerted effort should be made to put the brakes on this."

The report was published online recently in the journal JAMA Network Open.

More information

The American Kidney Foundation has more on chronic kidney disease.